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Systemic in vivo distribution of activatable cell penetrating peptides is superior to cell penetrating peptides

Cell penetrating peptides (CPPs) have been developed as vehicles for payload delivery into cells in culture and in animals. However several biologic features limit their usefulness in living animals. Activatable cell penetrating peptides (ACPPs) are polycationic CPPs whose adsorption and cellular up...

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Detalhes bibliográficos
Main Authors: Aguilera, Todd A., Timmers, Margaret M., Olson, Emilia S., Jiang, Tao, Tsien, Roger Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796831/
https://ncbi.nlm.nih.gov/pubmed/20023744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b904878b
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