The KRAS Promoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-forming GA-element

The murine KRAS promoter contains a G-rich nuclease hypersensitive element (GA-element) upstream of the transcription start site that is essential for transcription. Pulldown and chromatin immunoprecipitation assays demonstrate that this GA-element is bound by the Myc-associated zinc finger (MAZ) an...

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Hlavní autoři: Cogoi, Susanna, Paramasivam, Manikandan, Membrino, Alexandro, Yokoyama, Kazunari K., Xodo, Luigi E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903372/
https://ncbi.nlm.nih.gov/pubmed/20457603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.101923
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