טוען...
Bortezomib-induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 MAPK pathway
Esophageal squamous cell carcinoma (ESCC) is an exceptionally drug resistant tumor with a five-year survival rate <5%. From an initial drug screen we identified bortezomib as having robust activity in ESCC lines. Mechanistically, bortezomib induced a G2/M phase cell cycle arrest and p53-independe...
שמור ב:
| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903039/ https://ncbi.nlm.nih.gov/pubmed/18790767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0391 |
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