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The Absence of the Pro-antioxidant Transcription Factor Nrf2 Exacerbates Experimental Autoimmune Encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease characterized by peripheral activation of CD4(+) T cells that migrate into the central nervous system (CNS) and mount an autoimmune neuroinflammatory attack on myelin and oligodendrocytes. Secondary to these events, however equally destructive, is the...

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Detalhes bibliográficos
Main Authors: Johnson, Delinda A., Amirahmadi, Sara, Ward, Charlotte, Fabry, Zsuszanna, Johnson, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902921/
https://ncbi.nlm.nih.gov/pubmed/19910389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp274
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