Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis

PURPOSE: Optic neuritis, inflammation of the optic nerve, is experienced by most patients with multiple sclerosis (MS) and is typically characterized by episodes of acute, monocular vision loss. These episodes of inflammation can lead to damage or degeneration of the retinal ganglion cells (RGCs), t...

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Veröffentlicht in:Mol Vis
Hauptverfasser: Larabee, Chelsea M., Desai, Shruti, Agasing, Agnieshka, Georgescu, Constantin, Wren, Jonathan D., Axtell, Robert C., Plafker, Scott M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204460/
https://ncbi.nlm.nih.gov/pubmed/28050123
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