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Absence of the Cellular Prion Protein Exacerbates and Prolongs Neuroinflammation in Experimental Autoimmune Encephalomyelitis

Although the physiological roles of the cellular prion protein (PrP(C)) remain to be fully elucidated, PrP(C) has been proposed to represent a potential regulator of cellular immunity. To test this hypothesis, we evaluated the consequences of PrP(C) deficiency on the course of experimental autoimmun...

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Detalhes bibliográficos
Main Authors: Tsutsui, Shigeki, Hahn, Jennifer N., Johnson, Trina A., Ali, Zenobia, Jirik, Frank R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543071/
https://ncbi.nlm.nih.gov/pubmed/18815152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071062
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