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Validation of a Preclinical Spinal Safety Model: Effects of Intrathecal Morphine in the Neonatal Rat
BACKGROUND: Preclinical studies demonstrate increased neuroapoptosis after general anesthesia in early life. Neuraxial techniques may minimize potential risks, but there has been no systematic evaluation of spinal analgesic safety in developmental models. We aimed to validate a preclinical model for...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902725/ https://ncbi.nlm.nih.gov/pubmed/20526189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181dcd6ec |
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