Relations between brain tissue loss, CSF biomarkers and the ApoE genetic profile: A longitudinal MRI study

Previously it was reported that Alzheimer's disease (AD) patients have reduced amyloid (Aβ(1-42)) and elevated total tau (t-tau) and phosphorylated tau (p-tau(181p)) in the cerebrospinal fluid (CSF), suggesting that these same measures could be used to detect early AD pathology in healthy elder...

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Detalhes bibliográficos
Main Authors: Tosun, Duygu, Schuff, Norbert, Truran-Sacrey, Diana, Shaw, Leslie M., Trojanowski, John Q., Aisen, Paul, Peterson, Ronald, Weiner, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902689/
https://ncbi.nlm.nih.gov/pubmed/20570401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.04.030
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