CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders

β-amyloid (Aβ) plaque accumulation is a hallmark of Alzheimer's disease (AD). It is believed to start many years prior to symptoms and is reflected by reduced cerebrospinal fluid (CSF) levels of the peptide Aβ1–42 (Aβ42). Here we tested the hypothesis that baseline levels of CSF proteins involv...

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Autores principales: Mattsson, N, Insel, P, Nosheny, R, Zetterberg, H, Trojanowski, J Q, Shaw, L M, Tosun, D, Weiner, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756294/
https://ncbi.nlm.nih.gov/pubmed/23962923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2013.69
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