CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders

β-amyloid (Aβ) plaque accumulation is a hallmark of Alzheimer's disease (AD). It is believed to start many years prior to symptoms and is reflected by reduced cerebrospinal fluid (CSF) levels of the peptide Aβ1–42 (Aβ42). Here we tested the hypothesis that baseline levels of CSF proteins involv...

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Detalhes bibliográficos
Main Authors: Mattsson, N, Insel, P, Nosheny, R, Zetterberg, H, Trojanowski, J Q, Shaw, L M, Tosun, D, Weiner, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756294/
https://ncbi.nlm.nih.gov/pubmed/23962923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2013.69
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