CSF Biomarker and PIB-PET–Derived Beta-Amyloid Signature Predicts Metabolic, Gray Matter, and Cognitive Changes in Nondemented Subjects

Beta-amyloid (Aβ) is a histopathological hallmark of Alzheimer’s disease dementia, but high levels of Aβ in the brain can also be found in a substantial proportion of nondemented subjects. Here we investigated which 2-year rate of brain and cognitive changes are present in nondemented subjects with...

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Detalhes bibliográficos
Main Authors: Ewers, Michael, Insel, Philip, Jagust, William J., Shaw, Leslie, Trojanowski J, John Q., Aisen, Paul, Petersen, Ronald C., Schuff, Norbert, Weiner, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500862/
https://ncbi.nlm.nih.gov/pubmed/22038908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhr271
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