Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects [Image: see text]

OBJECTIVE: To determine whether elderly normal APOE E2 (APOE2) carriers exhibit slower rates of hippocampal atrophy and memory decline compared to APOE3/3 carriers. We also determined whether APOE2 carriers have less Alzheimer pathology as reflected by CSF biomarkers. METHODS: We included longitudin...

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Autors principals: Chiang, G.C., Insel, P.S., Tosun, D., Schuff, N., Truran-Sacrey, D., Raptentsetsang, S.T., Jack, C.R., Aisen, P.S., Petersen, R.C., Weiner, M.W.
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Neurology 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014234/
https://ncbi.nlm.nih.gov/pubmed/20980669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181ffe4d1
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