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PGE(2) decreases reactivity of human platelets by activating EP2 and EP4
INTRODUCTION: Platelet hyperreactivity associates with cardiovascular events in humans. Studies in mice and humans suggest that prostaglandin E(2) (PGE(2)) regulates platelet activation. In mice, activation of the PGE(2) receptor subtype 3 (EP3) promotes thrombosis, but the significance of EP3 in hu...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902561/ https://ncbi.nlm.nih.gov/pubmed/20451959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.04.003 |
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