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Increased dietary NaCl induces renal medullary PGE(2) production and natriuresis via the EP2 receptor

A high-NaCl diet induces renal medullary cyclooxygenase (COX)2 expression, and selective intramedullary infusion of a COX2 inhibitor increases blood pressure in rats on a high-salt diet. The present study characterized the specific prostanoid contributing to the antihypertensive effect of COX2. C57B...

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Bibliografiske detaljer
Main Authors: Chen, Jian, Zhao, Min, He, Wenjuan, Milne, Ginger L., Howard, Jocelyn R. H., Morrow, Jason, Hébert, Richard L., Breyer, Richard M., Chen, Jing, Hao, Chuan-Ming
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653111/
https://ncbi.nlm.nih.gov/pubmed/18632796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90253.2008
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