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PGE(2) decreases reactivity of human platelets by activating EP2 and EP4

INTRODUCTION: Platelet hyperreactivity associates with cardiovascular events in humans. Studies in mice and humans suggest that prostaglandin E(2) (PGE(2)) regulates platelet activation. In mice, activation of the PGE(2) receptor subtype 3 (EP3) promotes thrombosis, but the significance of EP3 in hu...

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書誌詳細
主要な著者: Smith, James P., Haddad, Elias V., Downey, Jason D., Breyer, Richard M., Boutaud, O.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902561/
https://ncbi.nlm.nih.gov/pubmed/20451959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.04.003
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