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Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis

Constitutive activation of signal transducer and activator of transcription 3 (Stat3) has been found in a variety of human malignancies and has been suggested to play an important role in carcinogenesis. Recently, our laboratory demonstrated that Stat3 is required for the development of skin tumors...

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Main Authors: Kataoka, Ken, Kim, Dae Joon, Carbajal, Steve, Clifford, John L., DiGiovanni, John
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902397/
https://ncbi.nlm.nih.gov/pubmed/18453544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn061
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