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Functional Comparison of Linker Histones in Xenopus Reveals Isoform-Specific Regulation by Cdk1 and RanGTP

H1 `linker' histones bind dynamically to nucleosomes and promote their compaction into chromatin fibers [1–4]. Developmental H1 isoforms are evolutionarily conserved, but their function, regulation, and post-translational modifications are poorly understood [5–7]. In Xenopus egg extracts, the e...

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Bibliographic Details
Main Authors: Freedman, Benjamin S., Heald, Rebecca
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902237/
https://ncbi.nlm.nih.gov/pubmed/20471264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.04.025
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