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Identification of different roles for RanGDP and RanGTP in nuclear protein import.

The importin-alpha/beta heterodimer and the GTPase Ran play key roles in nuclear protein import. Importin binds the nuclear localization signal (NLS). Translocation of the resulting import ligand complex through the nuclear pore complex (NPC) requires Ran and is terminated at the nucleoplasmic side...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Görlich, D, Panté, N, Kutay, U, Aebi, U, Bischoff, F R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452303/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8896452/
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