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Identification of different roles for RanGDP and RanGTP in nuclear protein import.

The importin-alpha/beta heterodimer and the GTPase Ran play key roles in nuclear protein import. Importin binds the nuclear localization signal (NLS). Translocation of the resulting import ligand complex through the nuclear pore complex (NPC) requires Ran and is terminated at the nucleoplasmic side...

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Bibliografske podrobnosti
Main Authors: Görlich, D, Panté, N, Kutay, U, Aebi, U, Bischoff, F R
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC452303/
https://ncbi.nlm.nih.gov/pubmed/8896452
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