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NF-kappaB is involved in SHetA2 circumvention of TNF-alpha resistance, but not induction of intrinsic apoptosis
Treatment of cancer with tumor necrosis factor-α (TNFα) is hindered by resistance and toxicity. The Flexible Heteroarotinoid (Flex-Het), SHetA2, sensitizes resistant ovarian cancer cells to TNFα-induced extrinsic apoptosis, and also induces intrinsic apoptosis as a single agent. This study tested th...
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| Main Authors: | , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902153/ https://ncbi.nlm.nih.gov/pubmed/20032777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283350e43 |
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