Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo

Flexible heteroarotinoids (Flex-Hets) compounds regulate growth, differentiation and apoptosis in cancer cells. The hypothesis of this study was that the lead Flex-Het, SHetA2, inhibits angiogenesis by blocking cytokine release from cancer cells. SHetA2 altered secretion of thrombospondin-4 (TSP-4),...

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Detalhes bibliográficos
Main Authors: Myers, Tashanna, Chengedza, Shylet, Lightfoot, Stan, Pan, Yanfang, Dedmond, Daynelle, Cole, Lauren, Tang, Yuhong, Benbrook, Doris M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Preclinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701494/
https://ncbi.nlm.nih.gov/pubmed/18802666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-008-9175-7
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