IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

Emerging evidence supports the concept that T helper type 17 (T(H)17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. Interleukin-22 (IL-22) and IL-17A are both effector cytokines produced by the T(H)17 lineage, and both were crucial...

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Detalhes bibliográficos
Main Authors: Aujla, Shean J, Chan, Yvonne R, Zheng, Mingquan, Fei, Mingjian, Askew, David J, Pociask, Derek A, Reinhart, Todd A, McAllister, Florencia, Edeal, Jennifer, Gaus, Kristi, Husain, Shahid, Kreindler, James L, Dubin, Patricia J, Pilewski, Joseph M, Myerburg, Mike M, Mason, Carol A, Iwakura, Yoichiro, Kolls, Jay K
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901867/
https://ncbi.nlm.nih.gov/pubmed/18264110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1710
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