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IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
Emerging evidence supports the concept that T helper type 17 (T(H)17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. Interleukin-22 (IL-22) and IL-17A are both effector cytokines produced by the T(H)17 lineage, and both were crucial...
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| Главные авторы: | , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901867/ https://ncbi.nlm.nih.gov/pubmed/18264110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1710 |
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