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Th17 cells and Mucosal Host Defense
Th17 cells are a new lineage of T-cells that are controlled by the transcription factor RORγt and develop independent of GATA-3, T-bet, Stat 4 and Stat 6. Novel effector molecules produced by these cells include IL-17A, IL-17F, IL-22, and IL-26. IL-17RA binds IL-17A and IL-17F and is critical for ho...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2293278/ https://ncbi.nlm.nih.gov/pubmed/18054248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2007.10.009 |
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