IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

Emerging evidence supports the concept that T helper type 17 (T(H)17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. Interleukin-22 (IL-22) and IL-17A are both effector cytokines produced by the T(H)17 lineage, and both were crucial...

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Détails bibliographiques
Auteurs principaux: Aujla, Shean J, Chan, Yvonne R, Zheng, Mingquan, Fei, Mingjian, Askew, David J, Pociask, Derek A, Reinhart, Todd A, McAllister, Florencia, Edeal, Jennifer, Gaus, Kristi, Husain, Shahid, Kreindler, James L, Dubin, Patricia J, Pilewski, Joseph M, Myerburg, Mike M, Mason, Carol A, Iwakura, Yoichiro, Kolls, Jay K
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901867/
https://ncbi.nlm.nih.gov/pubmed/18264110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1710
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