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Targeted Intracellular Delivery of Antisense Oligonucleotides Via Conjugation With Small Molecule Ligands
Selective delivery of antisense or siRNA oligonucleotides to cells and tissues via receptor-mediated endocytosis is becoming an important approach for oligonucleotide-based pharmacology. In most cases receptor targeting has been attained using antibodies or peptide-type ligands. Thus there are few e...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901626/ https://ncbi.nlm.nih.gov/pubmed/20550198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja102635c |
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