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Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice
The slow growth rate and genetic intractability of tubercle bacilli has hindered progress toward understanding tuberculosis, one of the most frequent causes of death worldwide. We overcame this roadblock through development of near-infrared (NIR) fluorogenic substrates for β-lactamase, an enzyme exp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901431/ https://ncbi.nlm.nih.gov/pubmed/20566877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000643107 |
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