In vitro non-homologous DNA end joining assays—The 20th anniversary

DNA double-strand breaks (DSBs) are the most serious forms of DNA damage in cells. Unrepaired or misrepaired DSBs account for some of the genetic instabilities that lead to mutations or cell death, and consequently, to cancer predisposition. In human cells non-homologous DNA end joining (NHEJ) is th...

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Main Authors: Pastwa, Elzbieta, Somiari, Richard I., Malinowski, Mariusz, Somiari, Stella B., Winters, Thomas A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901157/
https://ncbi.nlm.nih.gov/pubmed/19110069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2008.11.007
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