Coilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joining

Coilin is a nuclear protein that plays a role in Cajal body formation. The function of nucleoplasmic coilin is unknown. Here we report that coilin interacts with Ku70 and Ku80, which are major players in the DNA repair process. Ku proteins compete with SMN and SmB′ proteins for coilin interaction si...

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Bibliographic Details
Main Authors: Velma, Venkatramreddy, Carrero, Zunamys I, Cosman, Angela M., Hebert, Michael D.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000556/
https://ncbi.nlm.nih.gov/pubmed/21070772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.11.004
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