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Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures
DNA double-strand breaks (DSBs) are a serious threat to the cell, for if not or miss-repaired, they can lead to chromosomal aberration, mutation and cancer. DSBs in human cells are repaired via non-homologous DNA end joining (NHEJ) and homologous recombination repair pathways. In the former process,...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Sociedade Brasileira de Genética
2010-01-01
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| Edice: | Genetics and Molecular Biology |
| Témata: | |
| On-line přístup: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200027 |
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