Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining

In mammalian cells, DNA double-strand breaks (DSBs) are primarily repaired by nonhomologous end joining (NHEJ). The current model suggests that the Ku 70/80 heterodimer binds to DSB ends and recruits DNA-PK(cs) to form the active DNA-dependent protein kinase, DNA-PK. Subsequently, XRCC4, DNA ligase...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hendrickson, Cynthia L., Purkayastha, Shubhadeep, Pastwa, Elzbieta, Neumann, Ronald D., Winters, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919755/
https://ncbi.nlm.nih.gov/pubmed/20706599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/823917
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados