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Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
Frontotemporal lobar degeneration is a fatal neurodegenerative disease that results in progressive decline in behavior, executive function and sometimes language. Disease mechanisms remain poorly understood. Recently, however, the DNA- and RNA-binding protein TDP-43 has been identified as the major...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900863/ https://ncbi.nlm.nih.gov/pubmed/18223198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn023 |
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