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Kinesin’s light chains inhibit the head- and microtubule-binding activity of its tail

Kinesin-1 is a microtubule-based motor comprising two heavy chains (KHCs) and two light chains (KLCs). Motor activity is precisely regulated to avoid futile ATP consumption and to ensure proper intracellular localization of kinesin-1 and its cargoes. The KHC tail inhibits ATPase activity by interact...

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Bibliografske podrobnosti
Main Authors: Wong, Yao Liang, Rice, Sarah E.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900695/
https://ncbi.nlm.nih.gov/pubmed/20547877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005854107
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