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Microtubule-associated Protein-like Binding of the Kinesin-1 Tail to Microtubules

The kinesin-1 molecular motor contains an ATP-dependent microtubule-binding site in its N-terminal head domain and an ATP-independent microtubule-binding site in its C-terminal tail domain. Here we demonstrate that a kinesin-1 tail fragment associates with microtubules with submicromolar affinity. B...

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Detalhes bibliográficos
Main Authors: Seeger, Mark A., Rice, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832967/
https://ncbi.nlm.nih.gov/pubmed/20071331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068247
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