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Kinesin’s light chains inhibit the head- and microtubule-binding activity of its tail
Kinesin-1 is a microtubule-based motor comprising two heavy chains (KHCs) and two light chains (KLCs). Motor activity is precisely regulated to avoid futile ATP consumption and to ensure proper intracellular localization of kinesin-1 and its cargoes. The KHC tail inhibits ATPase activity by interact...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900695/ https://ncbi.nlm.nih.gov/pubmed/20547877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005854107 |
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