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Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
Recombinant proteins are important therapeutics due to potent, highly specific, and nontoxic actions in vivo. However, they are expensive medicines to manufacture, chemically unstable, and difficult to administer with low patient uptake and compliance. Small molecule drugs are cheaper and more bioav...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900680/ https://ncbi.nlm.nih.gov/pubmed/20543141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002498107 |
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