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Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
Recombinant proteins are important therapeutics due to potent, highly specific, and nontoxic actions in vivo. However, they are expensive medicines to manufacture, chemically unstable, and difficult to administer with low patient uptake and compliance. Small molecule drugs are cheaper and more bioav...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900680/ https://ncbi.nlm.nih.gov/pubmed/20543141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002498107 |
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