High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases

We report here an efficient method for targeted mutagenesis of Arabidopsis genes through regulated expression of zinc finger nucleases (ZFNs)—enzymes engineered to create DNA double-strand breaks at specific target loci. ZFNs recognizing the Arabidopsis ADH1 and TT4 genes were made by Oligomerized P...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhang, Feng, Maeder, Morgan L., Unger-Wallace, Erica, Hoshaw, Justin P., Reyon, Deepak, Christian, Michelle, Li, Xiaohong, Pierick, Christopher J., Dobbs, Drena, Peterson, Thomas, Joung, J. Keith, Voytas, Daniel F.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900673/
https://ncbi.nlm.nih.gov/pubmed/20508152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914991107
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares