Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases

Tandemly arrayed genes (TAGs) or gene clusters are prevalent in higher eukaryotic genomes. For example, approximately 17% of genes are organized in tandem in the model plant Arabidopsis thaliana. The genetic redundancy created by TAGs presents a challenge for reverse genetics. As molecular scissors,...

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Main Authors: Qi, Yiping, Li, Xiaohong, Zhang, Yong, Starker, Colby G., Baltes, Nicholas J., Zhang, Feng, Sander, Jeffry D., Reyon, Deepak, Joung, J. Keith, Voytas, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789795/
https://ncbi.nlm.nih.gov/pubmed/23979943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.006270
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