Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors

p53 is a central player in responses to cellular stresses and a major tumor suppressor. The identification of unique molecules within the p53 signaling network can reveal functions of this important transcription factor. Here, we show that brain-expressed RING finger protein (BERP) is a gene whose e...

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Autors principals: Cheung, Carol C., Yang, Caimei, Berger, Thorsten, Zaugg, Kathrin, Reilly, Patrick, Elia, Andrew J., Wakeham, Andrew, You-Ten, Annick, Chang, Ning, Li, Lijun, Wan, Qi, Mak, Tak Wah
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900672/
https://ncbi.nlm.nih.gov/pubmed/20543135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006529107
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