Hepatic tumor–stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge

The tumor–stroma crosstalk is a dynamic process fundamental in tumor development. In hepatocellular carcinoma (HCC), the progression of malignant hepatocytes frequently depends on transforming growth factor (TGF)-β provided by stromal cells. TGF-β induces an epithelial to mesenchymal transition (EMT...

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Detalhes bibliográficos
Main Authors: van Zijl, F, Mair, M, Csiszar, A, Schneller, D, Zulehner, G, Huber, H, Eferl, R, Beug, H, Dolznig, H, Mikulits, W
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900602/
https://ncbi.nlm.nih.gov/pubmed/19718050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.253
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