ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression

In human hepatocellular carcinoma (HCC), epithelial to mesenchymal transition (EMT) correlates with aggressiveness of tumors and poor survival. We employed a model of EMT based on immortalized p19(ARF) null hepatocytes (MIM), which display tumor growth upon expression of oncogenic Ras and undergo EM...

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Main Authors: Lahsnig, C, Mikula, M, Petz, M, Zulehner, G, Schneller, D, van Zijl, F, Huber, H, Csiszar, A, Beug, H, Mikulits, W
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900603/
https://ncbi.nlm.nih.gov/pubmed/19015638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.418
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