Nuclear β-Catenin Induces an Early Liver Progenitor Phenotype in Hepatocellular Carcinoma and Promotes Tumor Recurrence

Transforming growth factor-β cooperates with oncogenic Ras to activate nuclear β-catenin during the epithelial to mesenchymal transition of hepatocytes, a process relevant in the progression of hepatocellular carcinoma (HCC). In this study we investigated the role of β-catenin in the differentiation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zulehner, Gudrun, Mikula, Mario, Schneller, Doris, van Zijl, Franziska, Huber, Heidemarie, Sieghart, Wolfgang, Grasl-Kraupp, Bettina, Waldhör, Thomas, Peck-Radosavljevic, Markus, Beug, Hartmut, Mikulits, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797905/
https://ncbi.nlm.nih.gov/pubmed/20008139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090300
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados