Mesenchymal stem cells induce tumor stroma formation and epithelial-mesenchymal transition through SPARC expression in colorectal cancer

Tumor-stroma interactions serve a crucial role in the development of colorectal cancer (CRC), in which secreted protein acidic and rich in cysteine (SPARC) has been implicated. Due to interactions between cancer and stromal cells [mesenchymal stem cells (MSCs)], SPARC gene expression is markedly upr...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Naito, Toshikatsu, Yuge, Ryo, Kitadai, Yasuhiko, Takigawa, Hidehiko, Higashi, Yukihito, Kuwai, Toshio, Kuraoka, Kazuya, Tanaka, Shinji, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072806/
https://ncbi.nlm.nih.gov/pubmed/33907853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.8055
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