Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma

Interaction between tumor cells and stromal cells plays an important role in the growth and metastasis of colon cancer. We previously found that carcinoma‐associated fibroblasts (CAFs) expressed platelet‐derived growth factor receptor‐β (PDGFR‐β) and that PDGFR targeted therapy using imatinib or nil...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Takigawa, Hidehiko, Kitadai, Yasuhiko, Shinagawa, Kei, Yuge, Ryo, Higashi, Yukihito, Tanaka, Shinji, Yasui, Wataru, Chayama, Kazuaki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001714/
https://ncbi.nlm.nih.gov/pubmed/26865419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12907
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