Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma

Interaction between tumor cells and stromal cells plays an important role in the growth and metastasis of colon cancer. We previously found that carcinoma‐associated fibroblasts (CAFs) expressed platelet‐derived growth factor receptor‐β (PDGFR‐β) and that PDGFR targeted therapy using imatinib or nil...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Takigawa, Hidehiko, Kitadai, Yasuhiko, Shinagawa, Kei, Yuge, Ryo, Higashi, Yukihito, Tanaka, Shinji, Yasui, Wataru, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001714/
https://ncbi.nlm.nih.gov/pubmed/26865419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12907
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