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Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms

Monoacylglycerol lipase (MGL) and fatty acid amide hydrolase (FAAH) degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), respectively. Pharmacological inhibition of these enzymes in the periphery may elucidate the role of endocannabinoids in controlling nociceptive transm...

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Detalhes bibliográficos
Main Authors: Spradley, Jessica M., Guindon, Josée, Hohmann, Andrea G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900457/
https://ncbi.nlm.nih.gov/pubmed/20416378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.03.007
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