Wird geladen...

A B56γ mutation in lung cancer disrupts the p53-dependent tumor suppressor function of protein phosphatase 2A

Earlier studies have demonstrated both p53-dependent and -independent tumor suppressive functions of B56γ-specific protein phosphatase 2A (B56γ-PP2A). In the absence of p53, B56γ-PP2A can inhibit cell proliferation and cell transformation by an unknown mechanism. In the presence of p53, upon DNA dam...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Shouse, Geoffrey P., Nobumori, Yumiko, Liu, Xuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900437/
https://ncbi.nlm.nih.gov/pubmed/20473327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.161
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!