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A B56γ mutation in lung cancer disrupts the p53-dependent tumor suppressor function of protein phosphatase 2A
Earlier studies have demonstrated both p53-dependent and -independent tumor suppressive functions of B56γ-specific protein phosphatase 2A (B56γ-PP2A). In the absence of p53, B56γ-PP2A can inhibit cell proliferation and cell transformation by an unknown mechanism. In the presence of p53, upon DNA dam...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900437/ https://ncbi.nlm.nih.gov/pubmed/20473327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.161 |
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