ARSENIC TRIOXIDE DOWNREGULATES SPECIFICITY PROTEIN (Sp) TRANSCRIPTION FACTORS AND INHIBITS BLADDER CANCER CELL AND TUMOR GROWTH

Arsenic trioxide exhibits antiproliferative, antiangiogenic and proapoptotic activity in cancer cells, and many genes associated with these responses are regulated by specificity protein (Sp) transcription factors. Treatment of cancer cells derived from urologic (bladder and prostate) and gastrointe...

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Hauptverfasser: Jutooru, Indira, Chadalapaka, Gayathri, Sreevalsan, Sandeep, Lei, Ping, Barhoumi, Rola, Burghardt, Robert, Safe, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900380/
https://ncbi.nlm.nih.gov/pubmed/20435036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.04.027
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