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Heparan sulfate dependent signaling of fibroblast growth factor (FGF) 18 by chondrocyte-derived perlecan

Perlecan is a large multi-domain proteoglycan which is essential for normal cartilage development. In this study perlecan was localized in the pericellular matrix of hypertrophic chondrocytes in developing human cartilage rudiments. Perlecan immunopurified from medium conditioned by cultured human f...

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Detalles Bibliográficos
Main Authors: Chuang, Christine Y., Lord, Megan S., Melrose, James, Rees, Martin D., Knox, Sarah M., Freeman, Craig, Iozzo, Renato V., Whitelock, John M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900151/
https://ncbi.nlm.nih.gov/pubmed/20507176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1005199
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